Dr
Shamsuddin is Professor
of Pathology at
the University
of Maryland School
of Medicine in
Baltimore USA.
Since 1975, he
has been researching
the process of
cancer formation,
cancer prevention
and cancer treatment.
He has pioneered
the immune enhancing
and anti-cancer
actions of Inositol & Cal Mag
IP6 for
which he was awarded
the US & European
patents.
First performed
in Dr. Shamsuddin's
laboratory, experiments
on the anti-cancer
action of Inositol & Cal Mag
IP6 have
been subsequently
reproduced and
extended by scientists
around the world,
reconfirming these
fascinating findings.
Inositol & Cal Mag
IP6,
and the other inositol
phosphates i.e.
IP1,
IP2,
IP3,
IP4,
IP5 are
normally present
in all mammalian
cells.
IP3 is
a key molecule
responsible for
cellular signal
transduction, controlling
vital functions
including cell
proliferation and
differentiation.
IP6 can lose one
or more phosphate
(P) while inositol
can gain them.
Thus the combination
of Inositol & Cal Mag
IP6 could yield more
of the crucial
IP3. The theory
is: since i) all
cancers, irrespective
of their type and
origin have a common
defect of uncontrolled
cell proliferation,
ii)
IP3 is a key
regulator of cell
growth and iii)
Inositol & Cal Mag
IP6 yield
IP3, therefore,
Inositol & Cal Mag
IP6 should be effective
against many a
different types
of cancers, and
across species.
The proof can be
seen in "
About
IP6" and "
What's
New." Ongoing
research are providing
us with new information
about these intriguing
molecules, almost
every day.
Following Internship
in Massachusetts
and Residency training
in pathology in
Maryland, he was
certified by the
American Board
of Pathology in
1977. In 1980,
he received Ph.D.
degree from the
University of Maryland
for his work on
colon carcinogenesis.
He joined the faculty
of the University
of Maryland as
an Instructor in
1977, and rose
through the ranks
of Assistant Professor
and Associate Professor
to become a full
Professor in 1988.
For his excellence
in teaching, Professor
Shamsuddin received
the Best Teacher
award from the
medical students
many times, including
the coveted "Golden Apple Award" by
the American Medical
Students' Association
in 1999.
Dr. Shamsuddin's
research on cancer started at the time he began his doctoral dissertation,
in 1975. That work was based on his
theory of "field effect phenomenon" and resulted in
the subsequent invention
of a very simple, accurate and practical mass screening test for
cancers of the colorectum and
lung with
potential utility also for cancers of the breast, prostate, uterine
cervix, etc. The colorectal cancer test is already popular in
China where it is known as "Shams' Test." Dr. Shamsuddin's
book on this subject,
written for health care professionals is entitled Diagnostic Assays
for Colon Cancer [CRC Press, Boca Raton,
Florida 1991].
In mid 1985, Dr.
Shamsuddin started
his pioneering experiments on the anti-cancer property of inositol
and inositol hexaphosphate (
IP6) - natural
constituents of cereals
and legumes such as rice, corn, beans etc. For the next decade
and a half, he has reconfirmed and expanded
his groundbreaking
studies to show the efficacy of Inositol & Cal Mag
IP6 against different
cancers in various experimental models. Realizing
the enormous potential
for health benefits of Inositol & Cal Mag
IP6 for humans and the general
lack of this knowledge, he became most
instrumental in organizing
the First International Symposium of Disease Prevention by
IP6 and Other Rice Components in Kyoto,
Japan [June 8-9,
1998]. Dr. Shamsuddin's book on this "
IP6:
Nature's Revolutionary Cancer Fighter" by Kensington Publishing
Corporation, New
York, 1998, is written for the general public. Aside from these
Dr. Shamsuddin has contributed numerous book-chapters
and published over
200 scientific papers.
